ODF, the full name is orally disintegrating film. This is a new type of dosage form.
People put the membrane in the mouth, it will be absorbed with saliva, disintegrate quickly, so that the body can absorb it.
Compared with other products, this film product has the characteristics of fast absorption, easy to carry, long shelf life, and no need for other liquids to be used together.
This product is generally applicable to industries such as pharmaceuticals, health care products, food and cannabis derivatives.
Over the past few decades, the tendency toward innovative drug delivery systems has majorly increased attempts to ensure efficacy, safety and patient acceptability. As discovery and development of new chemical agents is a complex, expensive and time-consuming process, so recent trends are shifting toward designing and developing innovative drug delivery systems for existing drugs. Out of those, the drug delivery system being very eminent among is orally disintegrating films (ODFs).
These fast disintegrating films have superiority over fast disintegrating tablets as the latter are associated with the risks of choking and friability. This drug delivery system has numerous advantages over conventional fast disintegrating tablets.
Various approaches are employed for formulating ODFs and among which solvent casting and spraying methods are frequently used. Generally, hydrophilic polymers along with other excipients are used for preparing ODFs which allow films to disintegrate quickly releasing incorporated active pharmaceutical ingredient (API) within seconds. Orally disintegrating films have potential for business and market exploitation because of their myriad of benefits over orally disintegrating tablets.
Oral route of drug administration is a most preferred route due to its ease of administration, non-invasiveness, adaptability, patient compliance and acceptability. Bioadhesive mucosal dosage forms including adhesive tablets, gels and patches are outcomes of technological development. Among various dosage forms, the use of polymeric films for delivering medication into buccal cavity has developed great potential in recent era (Arya et al., 2010). Orally disintegrating films (ODFs), when placed on tongue, immediately hydrates by soaking saliva following disintegration and/or dissolution releasing active pharmaceutical agent from the dosage form (Chauhan et al., 2012). ODFs are kind of formulations which are commonly prepared using hydrophilic polymers enabling rapid dissolution upon contact with saliva. Oral disintegrating tablets (ODTs) and oral disintegrating films (ODFs) are the typical examples of orally disintegrating drug delivery systems.
The application of hemp in ODF is at a fresh stage. The CBD substances contained in each film are fixed, and the CBD components ingested each time are also fixed, which ensures that users will not over-ingest substances. At the same time, the rapid disintegration feature enables the beneficial ingredients to be quickly dissolved and absorbed.